A blank cell may mean a question was not answered, a measurement was unavailable, or the field did not apply. Treating all of those cases as zero can change the meaning of a calculation.

Decide how missing values are represented and explain the choice. Check whether a summary excludes them or replaces them with another value. The reason information is missing can matter as much as the amount missing.

Look at a few absent values in their original context before choosing a rule. Preserve distinctions that affect the question, and avoid filling gaps merely to make the table look complete. Honest incompleteness can be more informative than a tidy but misleading number.

A few starting points
  1. Ask why the value is absent.
  2. Document how calculations handle missing values.
  3. Avoid silently replacing every blank with zero.

Imagine a practical setting.

Consider a temperature record with a gap during an unavailable reading. Substituting zero would describe a physical observation that never happened.

Before the next experiment.

A column name can hide an assumption. Check units, missing values, and the counting rule before combining observations that only appear to be alike.

Follow a related question

Identify unnecessary transfers or repeated work.

Build with a little more restraint

Identify the claims that materially matter.

A plausible answer can still be wrong

Keep learning

Related background to continue exploring this subject.

NIST: statistical engineering NIST: the International System of Units
Explore a possibility